R

merlin stands for Mixed Effects Regression for LInear, Non-linear and user-defined models. The merlin packages implement the methodology described in the paper: Crowther MJ. Extended multivariate generalised linear and non-linear mixed effects models. arXiv:1710.02223. You can get the methods preprint here (or the easier to read software preprint here), which I recommend you read before trying out the accompanying software (note, merlin used to be called megenreg, and the syntax is out of date in the methods pre-print!

Simulation of simple and complex survival/time-to-event data The survsim packages implement the methodology described in the papers: Crowther MJ, Lambert PC. Simulating biologically plausible complex survival data. Statistics in Medicine 2013;32(23):4118-4134. and Crowther MJ, Lambert PC. Simulating complex survival data. The Stata Journal 2012;12(4):674-687. I recommend you read them before trying out the accompanying software. This page details the development of the package, both in terms of version histories and planned features to be added.

megenreg has been superseded by merlin - please visit the merlin pages here. The below is provided only for reference. Mixed Effects GENeralised REGression models The megenreg packages implement the methodology described in the paper: Crowther MJ. Extended multivariate generalised linear and non-linear mixed effects models. arXiv:1710.02223. You can get the preprint here, which I recommend you read before trying out the accompanying software. The software is being constantly developed and improved.